https://www.efimovlab.com/home daily 1.0 2026-03-30 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1649873401657-L4CBNIQLZ0PTLPM9UOGH/image-asset.jpeg Home https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1741728361249-24U7W9JO8NOLJW4C2ALG/Efimov+Lab.jpg Home https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1649873405510-H303TP7PU38AM681SE74/NIH+National+Heart%2C+Lung%2C+and+Blood+Institute.jpg Home https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1654803213604-V2JOSWBB00F6ACRK7HSZ/AHA+logo.png Home https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1654803221534-30KC3DXS3RYI8PLPEP13/leducq+foundation.png Home https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/2e488f3a-6b77-41fb-8c34-ef74a521da8b/Experiments+-+5.jpg Home - What we do Our Cardiovascular Engineering Laboratory conducts research in the field of cardiovascular engineering, biology and physiology, imaging and medical device development. Cardiovascular disease is the leading cause of death in the industrialized world. Sudden cardiac death occurs due to the development of fatal disturbances of cardiac rhythm known as arrhythmias. The research in the Efimov laboratory is focused on advancing our understanding of the fundamental mechanisms of arrhythmogenesis, and on developing novel diagnostic tools and lifesaving anti-arrhythmic therapies. We pursue both biological and device-based therapeutic strategies, including siRNA-mediated treatment, low-energy electrotherapy for arrhythmia, and stretchable and flexible electronic platforms. Our basic and applied research is particularly focused on investigation of the human heart physiology and pathophysiology, which provides a clinically relevant platform for novel theory development and high throughput drug screening for cardiac toxicity. https://www.efimovlab.com/news daily 0.75 2026-02-05 https://www.efimovlab.com/news/professor-igor-efimov-invested-as-american-academy-of-sciences-and-letters-member monthly 0.5 2026-02-05 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/04e2a945-da7d-4e11-9581-7ff38b925bf3/efimov-invested-as-american-academy-of-sciences-and-letters-member-body.jpg News - Professor Igor Efimov Invested as American Academy of Sciences and Letters Member - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/a-new-paper-on-age-and-sex-specific-modulation-of-human-cardiac-electrophysiology-by-doxorubicin-has-been-accepted-for-publication-by-the-journal-of-physiology monthly 0.5 2026-02-03 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/c3f558a8-b0a0-4b3c-8ce3-5aa6a80ba0cc/dox.jpg News - A New Paper on Age- and sex-specific modulation of human cardiac electrophysiology by doxorubicin has been accepted for publication by the Journal of Physiology - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/new-publication-a-promising-anti-arrhythmic-therapy-targeting-ryr2-tested-in-the-human-heart monthly 0.5 2026-01-30 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/3726ed4f-cd8a-4788-8358-ae3d7a12535f/blogpost.png News - New Publication: A Promising Anti-Arrhythmic Therapy Targeting RyR2 Tested in the Human Heart - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/mstp-student-charlie-stark-awarded-aha-predoctoral-fellowship monthly 0.5 2026-01-30 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/4c06b721-bb75-4248-8f8e-b6963d194600/Charlie-1.jpg News - MSTP Student Charlie Stark Awarded AHA Predoctoral Fellowship Charlie was awarded a Predoctoral Fellowship from the American Heart Association for his proposal “Cardiac Resynchronization with the World’s Smallest Pacemakers”. With this support of this fellowship, Charlie will develop supporting systems that enable the milli-pacemaker, named one of TIME magazine’s “Best Inventions of 2025”, to treat heart failure. https://www.efimovlab.com/news/eric-rytkin-md-phd-named-to-cardiovascular-business-forty-under-40-class-of-2025 monthly 0.5 2025-04-21 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/ad086609-5625-4d00-a584-0039756b6f6b/eric+blog.png News - Eric Rytkin, MD, PhD named to Cardiovascular Business' Forty Under 40 Class of 2025 - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/pacemaker-smaller-than-a-grain-of-rice-published-in-nature-and-featured-in-the-news monthly 0.5 2025-06-25 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/8f8e8fe9-8809-4fc6-84ae-7a7ac4ffabab/help-save-babies-born-heart-101546674.jpg-2.jpeg News - Pacemaker Smaller Than a Grain of Rice: Published in Nature and Featured in the News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/new-manuscript-in-science-advances-highlights-novel-soft-multimodal-optoelectronic-array-for-cardiac-mapping monthly 0.5 2025-03-19 https://www.efimovlab.com/news/dr-igor-efimov-honored-with-2025-ralph-lazzara-lectureship-award-by-heart-rhythm-society monthly 0.5 2024-09-06 https://www.efimovlab.com/news/micah-madrid-successfully-defended-his-phd monthly 0.5 2024-08-26 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/51e9fd50-81fa-46fd-9a94-31f590e37960/PhD+Defense+-+Micah+Madrid.jpg News - Micah Madrid successfully defended his PhD - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/dr-sharon-george-has-accepted-an-assistant-professor-position-at-the-university-of-pittsburgh monthly 0.5 2024-01-19 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/c01ecaef-1016-4222-9cab-cdef2fe270b6/20240118+-+SGeorge_Photo.jpg News - Dr. Sharon George has accepted an Assistant Professor position at the University of Pittsburgh - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/interview-dr-efimov-discusses-breakthrough-device-in-cardiac-research-with-newseria-a-news-agency-in-poland monthly 0.5 2023-10-24 https://www.efimovlab.com/news/campen-publishes-an-article-on-degradable-devices monthly 0.5 2023-10-18 https://www.efimovlab.com/news/new-manuscript-published-on-the-anti-arrhythmic-effects-of-dantrolene-in-human-hearts monthly 0.5 2023-10-04 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/d966201b-6e07-44ee-868c-cfce083473af/News+Post+2.jpg News - New Manuscript Published on the Anti-Arrhythmic Effects of Dantrolene in Human Hearts - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/new-manuscript-published-on-the-roles-of-p38a-and-p38b-mapk-in-anthracycline-cardiotoxicity monthly 0.5 2023-10-04 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/868bc143-45ad-4bda-be18-69ef00609e91/News+Post+1.jpg News - New Manuscript Published on the Roles of p38α and p38β MAPK in Anthracycline Cardiotoxicity - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/lab-members-develop-the-first-dissolvable-heart-monitor-and-pacer monthly 0.5 2023-08-03 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/8fb1ce84-462d-45e5-9c74-f4e3a90be814/absorbable-pacemaker-7.10.2023-e1688940203264.jpg News - Lab Members Develop the First Dissolvable Heart Monitor and Pacer - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/graphene-tattoo-treats-cardiac-arrhythmia-with-light monthly 0.5 2023-04-18 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/ee44a541-97e4-4f1c-9c92-bc7bbdd31313/tattoo1940__FitMaxWzk3MCw2NTBd.jpg News - Graphene ‘tattoo’ treats cardiac arrhythmia with light - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/dr-eric-rytkin-to-serve-as-an-associate-faculty-at-the-interventional-cardiology-crt2023-conference monthly 0.5 2023-08-03 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/4ae3084c-6854-4be0-9051-d1e6ad848a08/ritkin1.jpg News - Dr. Eric Rytkin to serve as an Associate Faculty at the interventional cardiology CRT2023 Conference - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/anna-gams-receives-jacc-clinical-ep-young-author-achievement-award monthly 0.5 2023-08-03 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/4fc793c7-4ca3-445d-8f76-b8656ff756c8/Anna+Gams+-+PhD+Student.JPG News - Anna Gams receives JACC Clinical EP Young Author Achievement Award - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/our-new-paper-has-just-been-published-by-nature-cardiovascular-research monthly 0.5 2023-08-03 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/577dcbbe-a622-4702-8c60-92f40d376966/1.17+Picture1.png News - New paper published by Nature Cardiovascular Research - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/a-new-paper-was-published-that-describes-the-molecular-and-functional-remodeling-of-cardiac-dual-pacemakers monthly 0.5 2023-08-03 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/3d567e0b-10fd-40ee-b4ea-62f81472e1ff/Picture1+112822.jpg News - Anna Gams published a new paper in JACC: CEP that describes the molecular and functional remodeling of cardiac pacemakers during heart failure - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/dr-yin-published-a-new-paper-on-nature-protocols-open-thoracic-surgical-implantation-of-cardiac-pacemakers-in-rats monthly 0.5 2023-08-03 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/469fa789-ee12-4a61-a203-1fcf652925aa/Picture1+11+22.jpg News - Rose Yin published a new paper in Nature Protocols titled "Open thoracic surgical implantation of cardiac pacemakers in rats" - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/battery-free-light-powered-pacemaker-may-improve-quality-of-life-for-heart-disease-patients monthly 0.5 2022-11-30 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/a8413645-d9bf-454c-8454-b63e75b15e5b/sciadv.abq7469-f1.jpg News - New paper in Science Advances: Battery-free, Light-powered Pacemaker may Improve Quality of Life for Heart Disease Patients - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/phd-student-anna-gams-has-defended-her-thesis monthly 0.5 2022-11-30 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/384ce35d-9694-4c7e-9a15-81e47ac4849e/20221031_-_Anna_PhD_Defense.jpg News - Anna Gams has defended her Ph.D. thesis! - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/phd-student-anna-gams-has-published-a-new-paper monthly 0.5 2022-11-17 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/9e314c55-59e2-448f-9b88-5895111c5407/Picture+for+-+PhD+Student+Anna+Gams+has+published+a+new+paper%21.jpg News - PhD Student Anna Gams has published a new paper! - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/dr-kedar-aras-has-accepted-an-assistant-professor-position-at-the-university-at-buffalo monthly 0.5 2023-08-03 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/a821cbe9-0bec-4600-a8d0-c915c1c63e8c/20220916+-+Dr.+Kedar+Aras+-+accepted+an+assistant+professor+position+at+the+University+at+Buffalo.jpg News - Dr. Kedar Aras has accepted an assistant professor position at the University at Buffalo - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/hardware-mappable-cellular-neural-networks-for-distributed-wavefront-detection-in-next-generation-cardiac-implants monthly 0.5 2022-07-14 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/113597e8-3889-425f-a461-afa4d4c5dc7f/GaHkNLCw.png News - Hardware-Mappable Cellular Neural Networks for Distributed Wavefront Detection in Next-Generation Cardiac Implants - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/rose-has-graduated monthly 0.5 2022-06-07 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/9f562ab7-5f9f-418d-9c81-489574cb0ddf/Picture1.jpg News - Rose Has Graduated! - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/smart-dissolving-pacemaker-communicates-with-body-area-sensor-and-control-network monthly 0.5 2022-06-14 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/6c56a783-2e32-42ad-a578-bd400cd34dbe/smart-dissolving-pacemaker-communicates-with-body-area-sensor-and-control-network2.jpg News - Smart, Dissolving Pacemaker Communicates with Body-area Sensor and Control Network - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news/dr-sharon-ann-george-awarded-the-american-heart-associations-career-development-award monthly 0.5 2022-05-24 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/7066b7df-31f2-4ac8-baf8-9b916c0d4d99/aha.jpg News - Dr Sharon Ann George Awarded the American Heart Association's Career Development Award! - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/mission-index-impact daily 0.75 2026-03-30 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/f5279d96-d65a-4695-b0ac-91066d948327/z5TC_Db4.jpeg Research Our Cardiovascular Engineering Laboratory conducts research in the field of cardiovascular engineering, biology and physiology, imaging and medical device development. Cardiovascular disease is the leading cause of death in the industrialized world. Sudden cardiac death occurs due to the development of fatal disturbances of cardiac rhythm known as arrhythmias. The research in the Efimov laboratory is focused on advancing our understanding of the fundamental mechanisms of arrhythmogenesis, and on developing novel diagnostic tools and lifesaving anti-arrhythmic therapies. We work on development of novel biological and devices therapies, including low energy electrotherapy of arrhythmia, stretchable and flexible electronics platform, and cell reprogramming strategies. Our basic and applied research is particularly focused on investigation of the human heart physiology and pathophysiology, which provides a clinically relevant platform for novel theory development and high throughput drug screening for cardiac toxicity. https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/fa20ace8-b014-4231-89f8-903711c3765a/graphene+1.png Research - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/cb34adf5-a028-4f3c-ab11-a63609da136c/graphene+2.png Research - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/97180778-0232-4174-a4d4-358abc304edd/multifunctional+flexible.png Research - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/024ad5ff-842e-41cd-b262-25b1e6b3edce/wireless+fully+implantable.png Research - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/de096dfd-544c-4e61-a61d-e4e570e12e38/device+on+rat+heart.png Research - A channel is in stimulating mode An optical photo of the device onto a rat heart https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/441fb450-7926-47fb-a00b-df0ce393e774/Picture1.png Research - Make it stand out (A) Optical image of the instrumented catheter inserted into a transparent heart model. (B) Schematic illustration of the stacked device arrays, complete with electrodes, temperature sensors, and pressure sensor. (C) Optical images of the electrode arrays transferred onto a silicone balloon catheter. (D) Optical images of the temperature sensors transferred onto a polyurethane balloon catheter. https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/4f3f4d97-0af1-424e-835b-48ff0326381b/20220725+-+Electrotherapy_v1.1+-+Kedar+Aras.png Research - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/8d85ba5a-5424-402e-bdb2-ad9546749728/Cardiooncology+Picture_Sharon.jpg Research - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/aafa668c-54f7-48e1-a067-575a4bd2bbb8/cardiac+genomics+anna.png Research - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/5e7c9a5d-50db-4bbd-bab1-41571f5a7648/Picture1.png Research - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.efimovlab.com/news-1 daily 0.75 2022-04-13 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1649873428050-IWYX2TPW15FOQBA119X1/DkExEcrX0AAqEqI.jpg News https://www.efimovlab.com/efimovlab daily 0.75 2022-04-27 https://www.efimovlab.com/efimovlab/2021/01/28/new-edition-of-cardiac-bioelectric-therapy-has-been-published monthly 0.5 2022-04-28 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1651155508878-4COC7M22U6HLZ7QTFZKS/Screen-Shot-2021-01-28-at-14.22.37.png Efimov Lab - New edition of Cardiac Bioelectric Therapy has been published! https://www.efimovlab.com/efimovlab/2020/09/30/catheter-integrated-soft-multilayer-electronic-arrays-for-multiplexed-sensing-and-actuation-during-cardiac-surgery monthly 0.5 2022-04-28 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1651155506542-F0SZZG2FODBZILMN3QGK/Screen-Shot-2020-09-30-at-1.44.25-AM.png Efimov Lab - “Catheter-integrated soft multilayer electronic arrays for multiplexed sensing and actuation during cardiac surgery” https://www.efimovlab.com/efimovlab/2020/09/02/rose-yin-2019-2020-accomplishments-graduate-student-highlight monthly 0.5 2022-04-28 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1651155504898-0FNIIPK792VYFNZONKWT/ROSE-e1599069224666.png Efimov Lab - Rose Yin, 2019-2020 Accomplishments, Graduate Student Highlight https://www.efimovlab.com/efimovlab/2020/09/02/2020-2021-stem-chateaubriand-fellowship-graduate-student-highlight-anna-gams monthly 0.5 2022-04-28 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1651155504800-XKBYXOEHJEGYK3DJ55G0/ANNA-e1599068117167.png Efimov Lab - 2020-2021 STEM Chateaubriand Fellowship, Anna Gams, Graduate Student Highlight! https://www.efimovlab.com/efimovlab/2020/08/24/congratulations-to-dr-aras-k99-award monthly 0.5 2022-04-28 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1651155505905-HO2WWGAWB0RMNI3QFPC4/DSC_2509-2-e1599067073478.jpg Efimov Lab - Congratulations to Dr. Aras for his K99 Award! https://www.efimovlab.com/efimovlab/2019/12/05/directsense-the-story-behind-the-innovation monthly 0.5 2022-04-28 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1651155505728-PC0K0K97R7M5HNLUH35B/Screen-Shot-2019-12-05-at-12.33.39-PM.png Efimov Lab - DIRECTSENSE: the Story Behind the Innovation https://www.efimovlab.com/efimovlab/2019/05/16/welcome-baby-avi monthly 0.5 2022-04-28 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1651155504797-007FABSM2L90IZXBAT02/Image-from-iOS.jpg Efimov Lab - Welcome Baby Avi https://www.efimovlab.com/efimovlab/2019/01/24/igor-efimov-awarded-2-5m-r01-grant-for-the-project-high-definition-conformal-electronics-for-vtvf monthly 0.5 2022-04-28 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1651155487920-JHH7VYUGT2OR5Z5AC9JU/Igor_Efimov_2018_WLA-6540-2lloorq.jpg Efimov Lab - Igor Efimov Awarded $2.5M R01 Grant for the Project "High-Definition Conformal Electronics for VT/VF" https://www.efimovlab.com/efimovlab/2019/01/24/two-fo-efimovs-undergraduate-students-publish-open-source-optocardiogaphy-system-in-nature-scientific-reports monthly 0.5 2022-04-28 https://images.squarespace-cdn.com/content/v1/625711e418cbc32bdec62f71/1651155496256-LWJPALLUPT8FRIJMNQGV/WhatsApp-Image-2019-01-24-at-10.45.14-AM-1mugxh6.jpeg Efimov Lab - Two fo Efimov's Undergraduate Students Publish Open-Source Optocardiogaphy System in Nature Scientific Reports https://www.efimovlab.com/efimovlab/2019/01/22/the-best-way-to-explain-the-research-is-through-dance monthly 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